What It Does:
Dermal-active formula targets signs of aging from three separate angles.
- Repairs: Helps boost natural collagen production
- Helps strengthen skin to reduce the look of wrinkles.
- Resurfaces: Accelerates cell turnover and smooths skin.
- Replumps: Hydrates skin and instantly minimizes the appearance of fine, dry lines.

High Performance Results:
- Effective as a laser on the look of lines and wrinkles.*
- Instant reduction in fine, dry lines.
In 10 days:
- 84% say deeper wrinkles look reduced.**
- 94% say skin feels smoother.**
- 90% say skin feels firmer.**
- 87% say skin feels more plumped.**
- 92% agree it’s gentle and non-irritating.**

In 4 weeks:
88% say skin looks lifted.***

In 16 weeks:
32% visible reduction in stubborn lines.****

*In a clinical study after 16 weeks, women who had one laser treatment showed the same improvement in the overall look of lines and wrinkles as those who used Smart Serum twice daily instead. Laser used: microablative, deka dot SmartSkin CO2™ (Cynosure, Westford, MA) with CO2 fractional tech.
**Consumer testing on 358 women.
***Consumer testing on 354 women.
****Upper lateral dynamic lines; clinical testing on 59 women after 16 weeks.

Key Ingredients:
- Peptides: Help boost skin’s natural collagen production for a smoother appearance. Our formula with CL1870 Laser Focus Complex™ includes “self-assembly,” “neuropeptide,” and “signaling peptides”:
- Palmitoyl tripeptide-1
- Acetyl hexapeptide-8
- Palmitoyl tetrapeptide-7
- Palmitoyl hexapeptide-12
- Advanced retinoid: The next generation of retinol, formulated for high-performance and gentle enough to use twice a day. Helps accelerate skin’s natural cell renewal to visibly reduce wrinkles.
- Hyaluronic acid: Instantly hydrates and plumps skin, helping minimize the look of fine, dry lines. Helps restore a youthful, supple appearance.
- Optimizing blend of caffeine and algae extract helps reduce irritation.

Formula Facts:
- Safe for sensitive skin.
- Dermatologist developed.
- Dermatologist tested.
- Fragrance-free.
- Allergy tested.


Free Of:
Fragrance-free

Use:
- Use twice a day, morning and night.
- Dispense 1 to 2 pumps onto fingertips.
- Spread serum all over clean face and neck, avoiding eye area.
- Follow with Clinique Smart Clinical Repair™ Wrinkle Correcting Cream.
- Daily sunscreen is imperative. Apply to face and neck in the AM after your moisturizer.
- Limit sun exposure while using and the week after.
- Do not use with other retinol products.

100 ml